ALDACE (Spironolactone) inhibits binding of aldosterone with its receptor at Na-K exchange site in the distal renal tubule. Thus, ALDACE inhibits the action of aldosterone and cause kidneys to promote sodium excretion along with water and conserves potassium.
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ALDACE (Spironolactone) inhibits binding of aldosterone with its receptor at Na-K exchange site in the distal renal tubule. Thus, ALDACE inhibits the action of aldosterone and cause kidneys to promote sodium excretion along with water and conserves potassium.